Research Article
Calenduloside E Ameliorates Myocardial Ischemia-Reperfusion Injury through Regulation of AMPK and Mitochondrial OPA1
Figure 8
CE improves OPA1 expression by activating the AMPK pathway. (a) Western blotting was used to analyze the changes in OPA1 and AMPK in response to CE and/or CC treatment. Compound C (CC), an AMPK pathway inhibitor, was added to the cardiomyocytes. β-Actin expression was examined as a protein loading control. (b) Mitochondrial membrane potential. (c) Changes of mitochondrial permeability transition pore opening. Data are presented as the from three independent experiments. ## vs. control; vs. H/R; vs. H/R; & vs. H/R+CE; && vs. H/R+CE.
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