Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner

Figure 11

Effect of WFA on the oxidative stress in fibrotic livers of WT and SIRT3 KO mice. (a) A T-AOC assay kit was used to examine the T-AOC in livers of each group. (b) An MDA assay kit was used to examine the MDA level in livers of each group. (c–g) The enzyme activities of HO-1, GR, total SOD, Mn-SOD, and Cu-Zn/SOD were measured in livers of each group. For the statistics of each panel in this figure, data are expressed as (). , , and .

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