Wenxin Keli Regulates Mitochondrial Oxidative Stress and Homeostasis and Improves Atrial Remodeling in Diabetic Rats

Figure 3

Effect of WXKL on epicardial electrical mapping and AF incidence in diabetic rats. Representative epicardial electrical mapping recorded of LA (a) or RA (e). Conduction velocity (CV) of LA (b) or RA (f), absolute inhomogeneity of LA (c) or RA (g), and inhomogeneity index of LA (d) or RA (h). (i) Parameters from EPS (SCL: sinus cycle length; AVWCL: atrioventricular Wenckebach cycle length). (j–l) Quantifications of interatrial conduction time (IACT), right atrium effective refractory period (RAERP), and left atrium effective refractory period (LAERP) at basic cycle lengths of 200, 150, and 100 ms. (m) Representative AF episodes induced by LA burst pacing. (n) Quantification of the inducibility of AF. Values are presented as . Compared with the control group, . Compared with the control group, . ^#Compared with the DM group, ; per group.

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