Research Article
Hexachloronaphthalene Induces Mitochondrial-Dependent Neurotoxicity via a Mechanism of Enhanced Production of Reactive Oxygen Species
Figure 1
Dose- and time-dependent effect of PCN67 on differentiated PC12 cells. The cells were treated with PCN67 concentration ranging from 0.001 μg/ml to 25 μg/ml for 24 h (a), 48 h (b), and 72 h (c). The half-maximal inhibitory concentration (IC50) was determined based on viability data obtained following 72 h treatment using nonlinear regression analysis (d). Cell viability in vehicle-treated cells was taken as 100%. and .
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