Hexachloronaphthalene Induces Mitochondrial-Dependent Neurotoxicity via a Mechanism of Enhanced Production of Reactive Oxygen Species

Figure 3

Toxicity of PCN67 depends on the maturation stage of primary hippocampal neurons. (a) The grayscale images of neuronal network photographed using an inverted phase microscope with a CCD camera. Scale bar 10 μm. (b) Neurons transfected with GFP plasmid cultured in defined media in the presence or absence of KCl (40 mM). KCl was added together with PCN67, and the images were taken 2 days later. (c) Quantification of axon length at DIV4 and (d) at DIV14. The longest neurite was measured. , , and .

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