Ganoderma lucidum Ameliorates Neurobehavioral Changes and Oxidative Stress Induced by Ethanol Binge Drinking

Table 1

Behavioral screening after acute administration of Aqueous Extract of Ganoderma lucidum (AEG1) by gavage in adult female Wistar rats in the acute oral toxicity test. A = EAGl 2000 mg/kg; B = EAGl 5000 mg/kg; and C = control groups. (+) Presence of the behavior signals; (0) Absence of behavior signals.

Signal	Time after administration
	30 min			1 h			2 h
	A	B	C	A	B	C	A	B	C
Lethargy	+	+	0	+	+	0	+	+	0
Ptosis	+	+	0	+	+	0	+	+	0
Agitation	+	+	0	+	0	0	+	0	0
Tremors	0	0	0	0	0	0	+	0	0
Increase of grooming	0	+	0	0	0	0	0	0	0
Increase of rearing	0	+	0	0	0	0	0	0	0
Signal	Days after administration
	Day 2			Day 4			Day 14
	A	B	C	A	B	C	A	B	C
Lethargy	+	+	0	0	+	0	0	0	0
Mortality	0	0	0	0	0	0	0	0	0