Vascular Inflammation Is a Risk Factor Associated with Brain Atrophy and Disease Severity in Parkinson’s Disease: A Case-Control Study

Table 4

Associations between vascular cell adhesion molecule-1 (VCAM-1) levels and disease severity scores after controlling for age and sex.

Disease severity score	Correlation coefficient	value
UPDRS I	0.461	0.005
UPDRS II	0.567	0.027
UPDRS III	0.535	0.008
UPDRS 176	0.563	0.005
HY-stage	0.418	0.047
SE-ADL	-0.604	0.002

The results of partial correlation analysis were illustrated as correlation coefficients and corresponding values (controlling for age and sex, Bonferroni corrected ). Abbreviations: PD: Parkinson’s disease; UPDRS: Unified Parkinson’s Disease Rating Scale; modified HY-stage: modified Hoehn and Yahr Staging Scale; SE-ADL: Schwab and England Activities of Daily Living Scale.