Resveratrol Inhibits Ischemia-Induced Myocardial Senescence Signals and NLRP3 Inflammasome Activation
RSV increased survival rate and decreased infarction area. (a) Survival rate after MI surgery ( in each of the NS and RSV groups, in each of the MI and MI+RSV groups, log rank for significant test), no significance has been tested between the NS and RSV groups, only the curve of the NS group was shown on pictures). (b) Representative Evans blue/TTC (2,3,5-triphenyltetrazolium chloride) staining of heart sections from the MI+NS and MI+RSV groups at the 7th day after myocardial infarction. (c) Quantitative analysis of infarct area in the MI+NS and MI+RSV groups (). (d) Representative PSR staining in the MI+NS and MI+RSV groups at the 7th day after myocardial infarction. (e) Calculated fibrosis area in the left ventricle (LV, ). (f) Representative Evans blue/TTC staining of mouse heart sections in the IR+NS and IR+RSV groups at the second day (mouse hearts were ischemic for 45 min and then for 24 h of reperfusion). (g) Quantitative analysis of infarct area and risk area after IR injury (-8). Two-tailed -test was used for significance test. Data are presented as the . # vs. the MI+NS group.