Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide-Treated RPE Cells through Activation of the Nrf2 Signaling Pathway

<div>Protective effect of phillyrin on apoptosis of RPE cells. (a) Morphological changes in the nuclei of RPE cells, as revealed via TUNEL staining. (b) Apoptosis of RPE cells treated with different concentrations of phillyrin, as detected using double staining of Annexin V-FITC/PI and flow cytometry. (c) Histogram of average cell fluorescence showing survival, early apoptotic, and late apoptotic cells. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide-Treated RPE Cells through Activation of the Nrf2 Signaling Pathway 