Research Article
Relationship between Oxidative Stress Biomarkers and Visual Field Progression in Patients with Primary Angle Closure Glaucoma
Table 3
Factors associated with progression of PACG as measured with visual field using Cox proportional hazards analysis.
| | Variable | Univariate | Multivariate | | HR (95% CI) | value | HR (95% CI) | value |
| | Age (year) | 1.018 (0.994-1.043) | 0.148 | NA | NA | | Female | 1.965 (1.007-3.833) | 0.048 | 2.228 (1.013-4.897) | 0.046 | | BMI (m2/kg) | 0.954 (0.858-1.061) | 0.389 | NA | NA | | SBP (mm Hg) | 1.003 (0.981-1.026) | 0.772 | NA | NA | | DBP (mm Hg) | 0.993 (0.962-1.026) | 0.684 | NA | NA | | Smoking (yes/no) | 1.418 (0.739-2.719) | 0.293 | NA | NA | | Drinking (yes/no) | 0.724 (0.347-1.510) | 0.389 | NA | NA | | IOP (mm Hg) | 0.993 (0.969-1.018) | 0.597 | NA | NA | | VCDR | 0.776 (0.183-3.296) | 0.731 | NA | NA | | CCT (mm) | 0.998 (0.991-1.005) | 0.598 | NA | NA | | ACD (cm) | 0.445 (0.198-0.996) | 0.049 | 0.483(0.196-1.190) | 0.114 | | AL (cm) | 0.804 (0.595-1.086) | 0.155 | NA | NA | | MD (dB) | 1.018 (0.979-1.059) | 0.365 | NA | NA | | GPX (U/L) | 0.993 (0.968-1.019) | 0.583 | NA | NA | | GR (U/L) | 0.994(0.970-1.018) | 0.606 | NA | NA | | SOD (U/mL) | 0.984 (0.975-0.995) | 0.005 | 0.983 (0.971-0.994) | 0.003 | | TAS | 0.055 (0.013-0.238) | <0.001 | 0.041 (0.008-0.218) | <0.001 | | MDA (umol/l) | 1.010 (1.003-1.017) | 0.008 | 1.010 (1.001-1.018) | 0.015 | | H2O2 (umol/l) | 1.013 (0.989-1.038) | 0.274 | NA | NA |
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