Oxidative Stress in Alzheimer’s Disease: In Vitro Therapeutic Effect of Amniotic Fluid Stem Cells Extracellular Vesicles

Figure 1

Effect of AFSC-EV supplementation on cell morphology of AD primary neurons in vitro. (a) Cells were incubated for 14 days with neurobasal medium 2% B27 containing AFSC-EV replaced once a week. Representative images with DAPI (blue) and βTubulinIII (red) or lamin A (red) signals of WT and FAD cells incubated or not with EV are shown. . In white squares are shown representative doubled magnification images. (b) Mean measures in of number, length, and diameter of neurites visualized in 10 fields for each condition are shown in graphs. value < 0.05; value < 0.01; value < 0.001.

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