Research Article
CIRBP Ameliorates Neuronal Amyloid Toxicity via Antioxidative and Antiapoptotic Pathways in Primary Cortical Neurons
Figure 1
CIRBP protected against Aβ-induced neurotoxicity in rat primary cortical neurons. (a) Western blot result shows CIRBP overexpression in cultured cortical neurons. vs. Ad-Con. (b) Cell viability was measured by MTT assay after treatment with 20 μM Aβ25-35. (c) Cell cytotoxicity was tested by LDH release assay after treatment with 20 μM Aβ25-35. vs. NC, vs. Ad-Con+Aβ25-35. (d) Cell viability was measured by MTT assay after iAβ1-42 adenovirus infection. (e) Cell cytotoxicity was tested by LDH release assay after iAβ1-42 adenovirus infection. vs. Ad-Con, , vs. Ad-Con+iAβ.
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