Autophagy in Age-Related Macular Degeneration: A Regulatory Mechanism of Oxidative Stress

Figure 3

Potential neuroprotective strategies targeting autophagy to prevent oxidative damage in AMD. AMD: age-related macular degeneration; RPE: retinal pigment epithelial; POS: photoreceptor outer segments; NFE2L2: nuclear factor erythroid 2-related factor 2; mTORC1: mammalian target of rapamycin complex 1; DPs: dietary polyphenols; DHA: n-3 PUFA docosahexaenoic acid (PUFA: polyunsaturated fatty acid); miR-29: microRNA-29; C3: the third complement component; βE-2: 17 β-estradiol.