Research Article
Dexmedetomidine Attenuates LPS-Induced Monocyte-Endothelial Adherence via Inhibiting Cx43/PKC-α/NOX2/ROS Signaling Pathway in Monocytes
Figure 1
Dexmedetomidine attenuates U937-HUVEC adhesion and inhibits VAL-4 and LFA-1 expression in U937 monocytes. (a) Effects of dexmedetomidine on U937-HUVEC adhesion when dexmedetomidine acts on U937 monocytes (, vs. control; # vs. the LPS group; & vs. the 0.1 nM dexmedetomidine group). (b) Effects of dexmedetomidine on VLA-4 and LFA-1 expressions in U937 monocytes (, vs. control; # vs. the LPS group; & vs. the 0.1 nM dexmedetomidine group).
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