Mitochondria-Associated Endoplasmic Reticulum Membranes (MAMs) and Their Prospective Roles in Kidney Disease

Table 1

Summary of the studies of MAMs’ involvement in kidney disease.

Mouse model	Cell types	Changes in MAMs	Kidney outcomes	Ref.
Adriamycin-induced nephropathy	Podocytes	Increased	Promoting podocyte apoptosis and increasing proteinuria	[126]
Streptozocin- (STZ-) induced diabetic mice	Tubular cells	Decreased	Promoting tubule apoptosis and accelerating kidney damage	[74]
Db/db mice	Podocytes	Increased	Promoting mitochondrial Ca^2+ overload and dysfunction, and exacerbating renal damage	[50]