Research Article

Apatinib, a Novel Tyrosine Kinase Inhibitor, Promotes ROS-Dependent Apoptosis and Autophagy via the Nrf2/HO-1 Pathway in Ovarian Cancer Cells

Table 1

VEGFR2 expression (cancer vs. normal) in other datasets of Oncomine.

DatasetsSubtype value-testFold change

Lu ovarianSerous0.007-3.921-1.62220
Mucinous0.007-3.453-1.5929
Endometrioid0.009-3.514-1.5629
Clear cell0.013-2.902-1.4807

TCGA ovarianSerous0.002-3.997-1.708586

Yoshihara ovarianSerous8.33E-4-3.460-2.57222

Adib ovarianSerous0.015-3.044-1.4066

Hendrix ovarianSerous0.033-2.580-1.13741
Mucinous0.118-1.313-1.07813
Endometrioid0.058-2.075-1.10737
Clear cell0.157-1.095-1.0658

Notes: the bold font indicates the difference was significant statistically. The negative value of fold change represents that VEGFR2 expression was downregulated. : number of patients.