Butterbur (Petasites hybridus) Extract Ameliorates Hepatic Damage Induced by Ovalbumin in Mice

Figure 4

Posttreatment with butterbur extract reduces MDA and TNF-α in ovalbumin-treated liver. Photomicrographs of liver sections stained immunohistochemically (a) no immune response against MDA in the control group, (b) no immune response in the group treated with butterbur extract (75 mg/kg), (c) intense immune response against MDA (arrows) in ovalbumin-treated group, (d) weak immune response against MDA in the group posttreated with butterbur extract to ovalbumin, (e) no immune response against TNF-α in the control group, (f) no immune response in the group treated with butterbur extract, (g) strong immune reactivity against TNF-α in the group treated with ovalbumin, and (h) weak immune reactivity against TNF-α in the group posttreated with butterbur extract to ovalbumin (ABC-method 400x;  μm).

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