Amarogentin from Gentiana rigescens Franch Exhibits Antiaging and Neuroprotective Effects through Antioxidative Stress

Figure 1

Chemical structure of amarogentin (AMA) (a), changes in the replicative lifespan of K6001 yeast after treatment with different concentrations of amarogentin (b). In the replicative lifespan assay, K6001 yeast cultured in galactose medium for 24 h. After that, it was spread on glucose agar plates with different concentrations of amarogentin or 10 μM RES as a positive control and incubated for 48 h. The randomly selected daughter cells produced by 40 mother cells were counted, and the survival curve was plotted for analysis. This process was repeated three times. , indicated significant difference as compared with the control ( and 0.01), respectively.

(a)

(b)