Amarogentin from Gentiana rigescens Franch Exhibits Antiaging and Neuroprotective Effects through Antioxidative Stress
Neuritogenesis activity of amarogentin in PC12 cells. (a) Percentage of cells with neurite outgrowth after treatment with indicated doses of amarogentin and amarogentin with NGF for 48 h. (b) Morphological changes in the neurite outgrowth of PC12 cells treated with negative control (0.5% DMSO) (A), positive control (40 ng/ml NGF) (B), amarogentin (3 μM) (C), NGF (1 ng/ml) (D), and amarogentin (3 μM) with NGF (1 ng/ml) (E). Each experiment was repeated thrice. The data are presented as . indicated significant and highly significant differences compared with the negative control group at .
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