Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis
Fucoidan reduces lipid levels and alleviates carotid atherosclerotic plaques progression. (a–c) Plasma lipid levels of total cholesterol, triglyceride, and LDL cholesterol in ApoE-/- mice. (d, f) Effects of fucoidan on carotid atherosclerotic plaques stained with HE and Oil Red O. (e, g) Summarized data of the lesion area and lipid content of carotid arteries. in each panel. Data are shown as the (). vs. control; # vs. model.
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