Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway

<div>NCA caused ROS to be produced and downregulated the activities of antioxidant enzymes in HepG2 cells. (a) ROS production in NCA-treated HepG2 cells was determined using a DCFH-DA fluorescence probe. (b) Statistical analysis of the green fluorescence intensity in NCA-treated HepG2 cells. (c) The activity of SOD in NCA-treated HepG2 cells was detected with the SOD kit. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway 

Figure 5 | Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway 