Thymoquinone Upregulates Catalase Gene Expression and Preserves the Structure of the Renal Cortex of Propylthiouracil-Induced Hypothyroid Rats
The glomeruli exhibit a very localized faint CD68 reaction (arrows) in both the control (a) and TQ (b) groups. The glomeruli in the hypothyroid group shows a strong widely distributed reaction (crossed arrow) with a periglomerular strong reaction (asterisk) (c). Some glomeruli are atrophied and totally replaced by CD68+ve cells (double headed arrow) (d). Hypothyroid rats administered TQ display a weaker and more localized glomerular and periglomerular reaction (arrowheads) in comparison with the hypothyroid group (e). The interstitium of both the control (f) and TQ (g) groups shows few CD68+ve cells (thick arrows). The hypothyroid group exhibit obvious increased the number of CD68+ve cells (empty arrow) (h). The hypothyroid+TQ group displays markedly decreased CD68+ve reaction (empty crossed arrow) (i) (CD68, ×400, scale ). CD68 expression in the renal mesangium (f) and interstitium (k) of the studied groups is represented.
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