Isokotomolide A from Cinnamomum kotoense Induce Melanoma Autophagy and Apoptosis In Vivo and In Vitro

Figure 2

Effects of Iso A and Sec A on the normal and melanoma cells. (a) HaCaT and Hs68 proliferations after the treatments of Iso A and Sec A for 24 h. (b) Quantifications of B16F10, MeWo, A2058, and A375 cell growth inhibitions in the above conditions, respectively. (c) Fluorescent images of Iso A and Sec A-induced acidic autophagic AVOs. Cells were stained with AO to detect with a fluorescence microscopy. At least three photos were taken in various view versions, and one was chosen as an example to be demonstrated. The data represented of three independent experiments performed. and . .

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