The Crosstalk between Calcium Ions and Aldosterone Contributes to Inflammation, Apoptosis, and Calcification of VSMC via the AIF-1/NF-<i>κ</i>B Pathway in Uremia

<div>The effect of calcium ions on inflammation, apoptosis, and calcification in VSMCs. (a) Calcified nodules of VSMCs were detected by alizarin red staining. (b) Apoptosis of VSMCs was evaluated by flow cytometry. (c) Production of aldosterone in VSMCs was regulated by calcium ions. (d) Production of MCP-1 in VSMCs was regulated by calcium ions. (e–h) Expression of AIF-1, CCR-2, and NF-<i>κ</i>B in VSMCs was evaluated by western blot assay. 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Oxidative Medicine and Cellular Longevity

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Figure 3

Figure 3: The Crosstalk between Calcium Ions and Aldosterone Contributes to Inflammation, Apoptosis, and Calcification of VSMC via the AIF-1/NF-<i>κ</i>B Pathway in Uremia 

Figure 3 | The Crosstalk between Calcium Ions and Aldosterone Contributes to Inflammation, Apoptosis, and Calcification of VSMC via the AIF-1/NF-κB Pathway in Uremia 