Hydroxy-α-sanshool Possesses Protective Potentials on H₂O₂-Stimulated PC12 Cells by Suppression of Oxidative Stress-Induced Apoptosis through Regulation of PI3K/Akt Signal Pathway

Figure 3

Effects of HAS on the in PC12 cells (×100). Cells were pretreated with vitamin C (100 μM) or HAS (15, 30, and 60 μM) for 2 h and then incubated in the presence of H₂O₂ (90 μM) for 4 h. was measured using a JC-1 assay kit and observed using a laser confocal microscopy under a 100× microscope. HAS: hydroxy-α-sanshool. The values were represented as the (). vs. the control group.