Hydroxy-α-sanshool Possesses Protective Potentials on H₂O₂-Stimulated PC12 Cells by Suppression of Oxidative Stress-Induced Apoptosis through Regulation of PI3K/Akt Signal Pathway

Figure 7

Effects of PI3K inhibitor LY294002 on the viability of PC12 cells (×100). The PC12 cells were pretreated with LY294002 (20 μM) or not for 1 hour; then cells were treated with HAS (60 μM) for 2 h, subsequently subjected to H₂O₂ (90 μM) for 4 h. HAS: hydroxy-α-sanshool; Norm.: normal. The values were represented as the (). vs. the control group.