Superoxide Dismutase Mimic, MnTE-2-PyP Enhances Rectal Anastomotic Strength in Rats after Preoperative Chemoradiotherapy

Figure 1

Diagram of experimental design. All rats underwent standard left colon resection and single-layer end-to-end anastomosis of the colon. Relaparotomy was performed after 7 days. CRT or CRT simulation was applied before the first operation as planned. Rats were injected with MnTE-2-PyP or doxycycline or PBS throughout the study as indicated. There were 15 rats in each group.