Superoxide Dismutase Mimic, MnTE-2-PyP Enhances Rectal Anastomotic Strength in Rats after Preoperative Chemoradiotherapy

<div>Effect of nonspecific MMP inhibitor doxycycline on anastomosis. (a) Anastomotic bursting pressure of rats in CRT groups (groups 4, 5, and 6). (b) Anastomotic hydroxyproline levels. (c, d) MMP-2 and MMP-9 levels were measured by ELISA after MnTE-2-PyP and doxycycline treatment (groups 4, 5, and 6). One-way ANOVA was used to calculate statistical significance. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Superoxide Dismutase Mimic, MnTE-2-PyP Enhances Rectal Anastomotic Strength in Rats after Preoperative Chemoradiotherapy 