Picroside II Improves Severe Acute Pancreatitis-Induced Intestinal Barrier Injury by Inactivating Oxidative and Inflammatory TLR4-Dependent PI3K/AKT/NF-κB Signaling and Improving Gut Microbiota

Figure 6

The effects of picroside II on the expression of TLR4-dependent phosphorylated PI3K/AKT/NF-κB. (a) Immunohistochemical analysis of TLR4 in the colon tissues. (b) Immunohistochemical analysis of p-P3IK in the colon tissues. (c) Immunohistochemical analysis of p-AKT in the colon tissues. (d) Immunohistochemical analysis of p-NF-κB in the small intestine. (e) Quantification of TLR4 levels. (f) Quantification of p-P3IK levels. (g) Quantification of p-AKT levels. (h) Quantification of p-NF-κB levels in 5 different immunohistochemical images. ^a vs. the CG group, ^b vs. the MG group, and ^c vs. the PG group. and for each group.

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