Prevention of Oxygen-Induced Inflammatory Lung Injury by Caffeine in Neonatal Rats

Figure 7

Hyperoxia and caffeine modulated gene expression of adenosine receptor subtypes (a) Adora1, (b) Adora2a, and (c) Adora2b. Quantification of lung homogenates was performed with qPCR for 3 days’ postnatal oxygen exposure (P3) and recovery (P3_P15) and 5 days’ postnatal oxygen exposure (P5) and recovery (P5_P15), respectively. Data are normalized to the level of rat pups exposed to normoxia at each time point (control 100%, white bars). -8/group. , , , and vs. control; ^##, ^###, and ^#### vs. hyperoxia (ANOVA, Kruskal-Wallis, Dunn’s post hoc test).