Oxymatrine Ameliorates Memory Impairment in Diabetic Rats by Regulating Oxidative Stress and Apoptosis: Involvement of NOX2/NOX4

<div>Effects of OMT on the expression of NOX in the brain tissues of diabetic rats. (a) NOX1, (b) NOX2, and (c) NOX4 mRNA expression levels. (d) NOX2 and (e) NOX4 protein expression levels. (f) NOX activity. 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172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg> vs. DM. DM: diabetes mellitus; OMT: oxymatrine; NOX: NADPH oxidase.</div>

Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Oxymatrine Ameliorates Memory Impairment in Diabetic Rats by Regulating Oxidative Stress and Apoptosis: Involvement of NOX2/NOX4 