Review Article

Oxidative Stress-Mediated Blood-Brain Barrier (BBB) Disruption in Neurological Diseases

Table 2

Potential biomarkers towards oxidative stress in neurological diseases.

BiomarkersDiseasesSourcesMethodsRef

NcRNAs
 miR-27bAISRat striatum and PC12 cellsqRT-PCR[313]
 miR-210ISIschemic penumbra regions of the right cerebral cortexqRT-PCR[314]
 miR-186ADHippocampal neuronal cellsqRT-PCR[315]
 lncRNA SOX21-AS1ADHippocampal neuronal cellsqRT-PCR[316]
Exosomes
α-SYN and DJ-1PDCSF and plasmaDifferential centrifugation[319]
CTRP9StrokePlasmaELISA[320]
Uric acidAISSerumBayer technician[322]
F2-isoprostanesAIS and ADPlasma, serum, urine, saliva, and cerebrospinal fluidGC-MS, LC-MS, and HPLC[325, 326]