A Preclinical Systematic Review of Curcumin for Protecting the Kidney with Ischemia Reperfusion Injury

Table 3

Risk of bias of the included studies.

Study	A	B	C	D	E	F	G	H	I	J	Total
Ni (2019) [24]	√	√	√			√				√	5
Chen (2018) [8]	√	√	√		√	√				√	6
Zhang (2018) [12]	√	√	√			√			√	√	6
Hu (2018) [23]	√	√	√			√			√	√	6
Kaur (2016) [13]	√	√	√			√			√	√	6
Liu (2016) [9]	√	√	√			√			√	√	6
Xu (2016) [21]	√	√	√			√				√	5
Najafi (2015) [25]	√	√	√			√			√	√	6
Chen (2013) [16]	√	√				√			√	√	5
Wang (2013) [19]	√	√	√			√				√	5
Hammad (2012) [15]	√	√	√			√			√	√	6
Niu (2012) [20]	√	√							√		3
Nian (2012) [18]	√	√	√			√			√		5
Tao (2012) [22]		√	√			√					3
Awad (2011) [14]	√	√	√			√			√	√	6
Li (2011) [17]	√	√	√			√					4
Rogers (2011) [11]	√	√	√			√				√	5
Bayrak (2008) [4]	√	√	√			√			√	√	6

Note: studies fulfilling the criteria of the following: A: peer-reviewed publication; B: control of temperature; C: random allocation to treatment or control; D: blinded induction of model (group randomly after modeling); E: blinded assessment of outcome; F: use of anesthetic without significant renoprotective activity or nephrotoxicity; G: appropriate animal model (aged, hyperlipemia or hypertensive); H: sample size calculation; I: compliance with animal welfare regulations (including three or more of the following points: preoperative anesthesia, postoperative analgesia, nutrition, disinfection, environment temperature, environment humidity, circadian rhythm, and euthanasia); J: statement of potential conflict of interest.