Research Article
Regulatory Effects of Nur77 on Airway Remodeling and ASMC Proliferation in House Dust Mite-Induced Asthma
Figure 4
Effect of Nur77 on ASM proliferation in HDM-induced asthma model. (a, b) Immunohistochemical staining of lung sections was conducted to assess the distribution and expression of α-SMA (a) and MMP-9 (b); scale bar: 50 μm. (c, d) Quantitative analysis of α-SMA (c) and MMP-9 (d) levels in lung tissues. (e, f) WB assay of phosphorylated AKT, total AKT, VEGF (e), phosphorylated ERK1/2, and total ERK1/2 (f) in lung tissues. , , and p <0.001. ns: not significant.
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