Resveratrol Mitigates Hippocampal Tau Acetylation and Cognitive Deficit by Activation SIRT1 in Aged Rats following Anesthesia and Surgery

<div>Activation of SIRT1 ameliorates cognitive impairment in aged rats of the POCD model. (a) The difference of escape latency in the MWM in five training days between control and sevoflurane+surgery groups. (b) The difference of platform crossing times in the probe trial of the MWM between control and sevoflurane+surgery groups. (c) The difference of escape latency in the MWM in five training days between resveratrol and sevoflurane+surgery+resveratrol groups. (d) The difference of platform crossing times in the probe trial of the MWM between resveratrol and sevoflurane+surgery+resveratrol groups. 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Oxidative Medicine and Cellular Longevity

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Figure 5

Figure 5: Resveratrol Mitigates Hippocampal Tau Acetylation and Cognitive Deficit by Activation SIRT1 in Aged Rats following Anesthesia and Surgery 