Overexpression of miR-506-3p Aggravates DBP-Induced Testicular Oxidative Stress in Rats by Downregulating ANXA5 via Nrf2/HO-1 Signaling Pathway

<div>Upregulation of miR-506-3p decreased the expression levels of Nrf2 and its downstream target genes in DBP-treated rats. (a) Immunohistochemical staining showed Nrf2 expression level of testis tissues in DBP-treated rats following miR-506-3p agomir and NC agomir injection. (b) Western blotting showed the expression levels of Nrf2 and its downstream target genes, HO-1, NQO1, and GST of testis tissues in DBP-treated rats following miR-506-3p agomir and NC agomir injection. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Overexpression of miR-506-3p Aggravates DBP-Induced Testicular Oxidative Stress in Rats by Downregulating ANXA5 via Nrf2/HO-1 Signaling Pathway 

Figure 3 | Overexpression of miR-506-3p Aggravates DBP-Induced Testicular Oxidative Stress in Rats by Downregulating ANXA5 via Nrf2/HO-1 Signaling Pathway 