Research Article
Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats
Figure 5
Eze reduced oxidative stress injury at 24 h after MCAO. (a) Representative microphotograph of DHE staining in the ischemic penumbra region. (b) Quantitative analysis of DHE-positive cells in the ischemic penumbra region. (c) The MDA level in the ischemic penumbra region. (d) Representative western blot band and quantitative analysis of Romo-1 expression. (e, f) Representative western blot bands and quantitative analyses of total-Nrf2 and nuclear-Nrf2 expression. vs. sham; # vs. vehicle. per group. DHE: dihydroethidium; Eze: Ezetimibe; MDA: malonaldehyde. .
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |