Research Article

Age-Related Maintenance of the Autophagy-Lysosomal System Is Dependent on Skeletal Muscle Type

Figure 3

Autophagy-related protein levels during aging in SOL and EDL: (a) protein levels, from left to right, of LC3-I, LC3-II, and LC3-II/LC3-I ratio; (b) ATG5; (c) p62. Ponceau S staining was used for normalization in densitometric quantification, and further old groups were normalized to the respective young (results in percentage). (d) On the lower right, the figure depicts representative immunoblot images. 5-6 mice were used from each group. Statistical significance was given as follows: and (Mann-Whitney test). Values are presented as