Beyond AREDS Formulations, What Is Next for Intermediate Age-Related Macular Degeneration (iAMD) Treatment? Potential Benefits of Antioxidant and Anti-inflammatory Apocarotenoids as Neuroprotectors

Table 1

Carotenoid content of various preparations as announced in the commercial advertisement (but not verified).

Product	Supplier	Carotenoid amount per day
AREDS1 original formula	—	B15
AREDS2 original formula	—	L 10, Z 2
AREDS2 Preser vision	Bausch & Lomb	L 10, Z 2
AREDS2 plus Zn free	Eyepromise	L 10, Z 10
AREDS2 with resveratrol	Fortifeye vitamins	L 10, Z 2, A 2
Advanced AREDS2 formula	Vitalux	L 10, Z 2
AREDS2	VitOptics	L 10, Z 2
Macula-Z	Horus Pharma	L 10, Z 2
Nutrof	Thea Pharma	L 10, Z 2
Vitalux plus	Alcon/Novartis	L 6, Z
Lutein+zeaxanthin	Piping rock	L 20, Z 1
Senior vision care complex	Piping rock	L 5, Z 8 μg
Ocuvite	Bausch & Lomb	L 5, Z 1
Suveal duo caps	Densmore Laboratoire	L 10, Z 2
Premium MariLut®	Time Sheet	L 10, M 10, Z 2
MacuGuard	Life Extension	L 10, M/Z 4, C
True vision	Nature City	L 10, M/Z 2, C 0.6
Eye protector	Pure Synergy	L 10, M/Z 5, A 2, C 3
Luteine crocine 20 mg	Essence pure	L 20, Z 2, C 0.6
AffronEye®	Pharmactive	C 0.6

A: astaxanthin; B: beta-carotene; C: crocin; L: lutein; M: meso-zeaxanthin; Z: zeaxanthin. Unless otherwise indicated, amounts are in mg.