Research Article

Protective Effect of Astragaloside IV on High Glucose-Induced Endothelial Dysfunction via Inhibition of P2X7R Dependent P38 MAPK Signaling Pathway

Figure 4

Effect of As-IV, SB203580 and P2X7R siRNA on endothelial dysfunction induced by high glucose (HG) in vitro. (a–f) Endothelium-dependent relaxation to ACh in the absence or presence of NO synthase inhibitor L-NAME (). vs. control group. ## vs. HG group.