Functional Redox Proteomics Reveal That Salvia miltiorrhiza Aqueous Extract Alleviates Adriamycin-Induced Cardiomyopathy via Inhibiting ROS-Dependent Apoptosis

Figure 3

(a) Safety of SMAE extract upon H9c2 cell viability was measured by the MTT assays. H9c2 cells were treated with various concentrations of SMAE (-axis). Data are of three independent experiments, carried out in triplicate (ns means no significance, ). (b) Viability of H9c2 cell was determined with or without 1 micro M ADR under exposure to 1.25 and 2.5 mg/mL SMAE, respectively. The quantified results were indicated by the bar chart. Results represent the of three independent experiments (, , ). (c) Synergistic effect of ADR and SMAE upon breast cancer cell (MCF-7) was determined with or without 1 micro M ADR under exposure to 2.5 mg/mL SMAE. The quantified results were indicated by the bar chart. Results represent the of three independent experiments (, , ).

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