The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling
4-HPPP induces apoptosis of NSCLC H1299 cells. The apoptosis induced by 4-HPPP was assessed using flow cytometry-based annexin V-PI staining. (a) H1299 cells were treated with 4-HPPP for the indicated time course. (b) The quantitative results of (a). (vehicle vs. 4-HPPP treatment) was considered statistically significant. ;.
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