Research Article
Semicarbazide-Sensitive Amine Oxidase Increases in Calcific Aortic Valve Stenosis and Contributes to Valvular Interstitial Cell Calcification
Figure 3
SSAO inhibition decreases calcification of human aortic valve interstitial cells. Valvular interstitial cells from aortic valves derived from patients were cultured in the absence and presence of 2.8 mM inorganic phosphate (Pi). (a) The SSAO inhibitor LJP1586 (1 μM) significantly inhibited calcification, measured as near-infrared fluorescence and quantified using Image Studio software. ; . (b) Valvular interstitial cells from one patient are exemplarily shown.
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