Mechanistic Insights into the Oxidized Low-Density Lipoprotein-Induced Atherosclerosis

Figure 2

LDL and Ox-LDL Structure. The hydrophobic core of LDL is made of around 170 triglycerides, 1500 cholesterol esters, a hydrophilic coat composed of 700 molecules of phospholipids, about 500 molecules of unesterified cholesterol, and a single large copy of the apolipoprotein B (ApoB) of 500 kDa. Gaining entrance into the endothelium, LDL gets oxidatively modified by ROS.