Cardiolipin Synthesis in Skeletal Muscle Is Rhythmic and Modifiable by Age and Diet

Figure 3

Identification of potential CL pathway genes regulated by ROR and the clock. (a) Genes encoding components required for CL synthesis were examined for oscillatory expression and promoter binding by circadian proteins were examined based on cross-comparison between published database and our own gene expression studies. In the middle column, we assign the symbols to reflect the possibility of circadian regulation of its expression based on existing data. N/A: data not available. (b) Real-time qPCR analysis of CL pathway genes in WT and RoracKD C2C12 cells over a circadian cycle (). Data are presented as . , , , two-way ANOVA with Bonferroni multiple comparisons test.

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