Cardiolipin Synthesis in Skeletal Muscle Is Rhythmic and Modifiable by Age and Diet

Figure 5

NOB treatment showed beneficial effects to partially restore CL gene expression and CL levels under the high-fat (HF) condition. Aged mice were fed with regular diet (as a control) or HF diet with or without NOB. (a) Effects of HF diet and NOB on the expression of CL synthesis genes (). Data are presented as . , , , one-way ANOVA with Dunnett’s multiple comparisons test. (b) Effects of HF diet and NOB on CL levels (). Note that the sample extraction was done by using PBS. Data are presented as . ^#, student’s -test.

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