Asiatic Acid Protects against Doxorubicin-Induced Cardiotoxicity in Mice

Figure 6

AA provided cardioprotection via the activation of AKT signaling pathway. (a, b) AKT and GSK3β in the H9c2 cells (). (c) The protein expression of Nrf2 (). (d) Cell viability in the cells (). (e) LDH release in vitro (). (f) SOD activity after DOX treatment (). (g) ROS production in the cells (). (h) Caspase 3 activity (). compared with the matched control.

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