Relationship between Decreased Serum Superoxide Dismutase Activity and Metabolic Syndrome: Synergistic Mediating Role of Insulin Resistance and <i>β</i>-Cell Dysfunction

<div>Linear trend tests for cellular aging and oxidative stress markers across metabolic syndrome component numbers. mtDNAcn and SOD activity exhibit a linear descending trend along with the progressive increase of MS component number, whereas other indicators did not show a statistically significant trend. Abbreviations: LTL: leukocyte telomere length; mtDNAcn: mitochondrial DNA copy number; 8-OHdG: 8-hydroxy-2-deoxyguanosine; SOD: superoxide dismutase; GR: glutathione reductase.</div>

Oxidative Medicine and Cellular Longevity

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Figure 2

Figure 2: Relationship between Decreased Serum Superoxide Dismutase Activity and Metabolic Syndrome: Synergistic Mediating Role of Insulin Resistance and <i>β</i>-Cell Dysfunction 

Figure 2 | Relationship between Decreased Serum Superoxide Dismutase Activity and Metabolic Syndrome: Synergistic Mediating Role of Insulin Resistance and β-Cell Dysfunction 