Effects of Early MSC Intervention on Preventing the Streptozotocin-Induced T1DM Progression in Mice

Figure 4

MSC-exosome-derived miR-148a-3p attenuates the inflammatory response initiation. Characterization of MSC-derived exosomes: the exosome morphology (a, scale bars: 100 nm), and the exosome concentration and size distribution (b), and Western blotting of the isolated exosome labeled with TSG101 and CD63 (c). The serum level of miR148a-3p of the MP group and none-MSC injection group, 72 h after MSC injection (d). The bioinformatics predictions of the base matching (e) and Luciferase reporter assay (f).

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