Oxidative Medicine and Cellular Longevity / 2020 / Article / Fig 4

Research Article

O-GlcNAcylation Is Essential for Autophagy in Cardiomyocytes

Figure 4

Enhanced O-GlcNAcylation stimulates autophagy in cardiomyocytes. (a) Left panel, western blot analysis for autophagy of wild-type neonatal cardiomyocytes with different treatments as indicated, using antibody against O-GlcNAc and LC3. GAPDH was detected as a loading control. Right panel, quantification of western blot results in the left panel, for each group. Significantly different; M.W.: molecular weight. (b) Left panel, western blot analysis of control or TMG-treated wild-type neonatal cardiomyocytes, using antibodies against O-GlcNAc and pATG16L. GAPDH was detected as a loading control. Right panel, quantification of western blot results in the left panel, for each group. Significantly different; M.W.: molecular weight.
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